Southwest Florida has experienced HABs such as red tide (karenia brevis) in prior years, which is most abundant during the summer and early fall months.

Florida Atlantic University researchers are asking residents of Cape Coral and surrounding communities to consider participating in a study to help evaluate the potential impacts of exposure to harmful algal blooms (HABs). Southwest Florida has experienced HABs such as red tide (karenia brevis) in prior years, which is most abundant during the summer and early fall months.  

Researchers will recruit volunteers on Tuesday, March 26, from noon to 4:30 p.m., and Wednesday, March 27, from 8 a.m. to noon, at the Public Works Department, 815 Nicholas Parkway East, Cape Coral. Appointments are available and walk-ins are welcome. Study participants will be asked to fill out a questionnaire and provide urine and blood samples as well as a nasal swab.

Human exposure to HABs comes from ingestion, direct skin contact or inhalation, and can lead to a variety of symptoms ranging from respiratory irritation to skin rashes and in severe cases liver damage.  Despite numerous occurrences of red tide and blue green algae in Florida waters, our understanding of the long-term health effects of exposure to these blooms remains limited.

With grant funding from the Florida Department of Health (FDOH), researchers from FAU’s Christine E. Lynn College of Nursing and Harbor Branch Oceanographic Institute are continuing this first-of-its-kind evaluation of both the short-term and potential long-term health effects among Florida residents. The “Long-term Effects of Exposure to Harmful Algal Blooms” (LEE-HABs) study uses a collaborative, multisite approach which also includes researchers from Florida Gulf Coast University.

This latest study expands upon prior studies conducted in 2016 and 2018, and previous FDOH studies from 2019 to 2020 and 2021 to 2022.  

“We have little data on health outcomes related to human exposure, despite the prevalence and intensity of harmful algal blooms in Southwest Florida,” said Rebecca S. Koszalinski, Ph.D., principal investigator and an associate professor in the Christine E. Lynn College of Nursing. “Understanding short- and long-term health impacts and outcomes is crucial to protecting the health of Floridians. By developing tools to measure concentrations of harmful algal blooms toxins in the environment and multiple human tissues, we will gain a better understanding of health-related outcomes and health care needs in Florida and elsewhere.”

The study also is the first to evaluate the potential effect of exposure to COVID-19. Researchers are exploring if there is a relationship between a history of being infected with COVID-19 and susceptibility to the effects of harmful algal blooms exposure.

The latest study involves a survey to identify the potential routes, duration and types of exposure to blooms through recreational and occupational activities. Researchers also will assess potential effects on individuals with pre-existing conditions such as asthma and chronic gastrointestinal disorders. Bloodwork including liver enzymes and renal markers also will be included in this study.

Algal toxin concentrations including microcystin and brevotoxin will be measured in blood, urine and nasal mucosa. The toxin levels also will be used to understand the dose-response relationships with self-reported respiratory, dermal and gastrointestinal symptoms. Urine and blood analyses will be conducted in collaboration with the United States Centers for Disease Control and Prevention, which is developing methodology to detect emerging algal toxins in human tissues.  

The study includes conducting environmental sampling of water and air to measure potential sources of exposure.

Researchers have developed a bio-repository and participant registry to store the data and samples in collaboration with FAU’s Clinical Research Unit within the FAU Division of Research. The purpose is to build an ongoing infrastructure to support the team’s long-term studies on the health effects of exposure to current and emerging harmful algal blooms toxins and serve as a resource for researchers around the state.

Malcolm McFarland, Ph.D., a research associate at FAU Harbor Branch, is co-principal investigator of the study. The research team also includes Michael Parsons, Ph.D., co-investigator and a professor of marine science at Florida Gulf Coast University.

For more information or to participate in the study, call or text 561-297-4631, or email Rebecca Koszalinski, Ph.D., at NurHAB@health.fau.edu. Community participants will receive up to $25 in gift cards as an incentive for participating in data collection activities each year.

-FAU-